Low Dose Naltrexone

Low Dose Naltrexone (LDN) is a compounded, low-dose formulation of the opioid receptor antagonist naltrexone. At lower dosages, it works differently than standard naltrexone—modulating the immune system and reducing chronic inflammation. It is used off-label for a range of conditions including autoimmune diseases, chronic pain, fibromyalgia and mood disorders. At low doses, LDN temporarily blocks opioid receptors, which causes the body to upregulate endorphin production—creating lasting anti-inflammatory and immune-calming effects.